Endocrine Abstracts

Adiponectin is a soluble protein produced solely by matured adipocytes. Adipogenesis contributes to the pathogenesis of GO in many ways including a direct effect on proptosis due to increased volume of mature adipocytes.The aim of the study was to estimate an influence of immunosupresive and anti-inflammatory treatment using systemic corticotherapy combined with orbital radiotherapy on serum adiponectin level in GO patients. The study was accepted by Eth...

54-year old woman with Graves’ disease was admitted to Endocrinology Department because of severe thyrotoxicosis and antithyroid drugs inolerance. The apathetic form of thyrotoxicosis was diagnosed; she lost 12 kg during 3 months and she had heavy muscle weakness. Previously she demonstrated allergic skin reactions (macular rushes) after both: Methimazole and Propylthiouracil. At admission her TSH was 0.001 mU/l, fT3 24 pg/ml, fT4 37 pmol/l. Lithium, propranolol and gluco...